BDBM50567047 CHEMBL4848254

SMILES CN(C)c1nccc(n1)-c1cnn2ncccc12

InChI Key InChIKey=IFLBFWBMAWIBBZ-UHFFFAOYSA-N

Data  15 IC50  17 Kd  1 Koff

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50567047   

TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50567047(CHEMBL4848254)
Affinity DataKd:  70nMAssay Description:Binding affinity to wild-type human full length CLK1 (M1 to I484 residues) expressed in bacterial expression system measured after 1 hr by competitiv...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50567047(CHEMBL4848254)
Affinity DataIC50:  319nMAssay Description:Inhibition of recombinant human CLK1 expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric scinti...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50567047(CHEMBL4848254)
Affinity DataKd:  5.40nMAssay Description:Binding affinity to human CLK1 assessed as equilibrium dissociation constant measured upto 240 min by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed